The role of the cell-cell adhesion molecule E-cadherin in large bowel tumour cell invasion and metastasis.


It has been suggested that the selective loss of E-cadherin expression can generate invasiveness in human carcinoma cells and might be a predictor of metastasis. Frozen sections of samples from 44 patients, 43 with suspected large bowel cancer and one with a liver recurrence were examined for E-cadherin expression using the antibody 6F9 specific for the… (More)
DOI: 10.1038/bjc.1993.169

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