The role of the aversive effects of drugs in self-administration: assessing the balance of reward and aversion in drug-taking behavior.

@article{Verendeev2013TheRO,
  title={The role of the aversive effects of drugs in self-administration: assessing the balance of reward and aversion in drug-taking behavior.},
  author={Andrey Verendeev and Anthony L. Riley},
  journal={Behavioural pharmacology},
  year={2013},
  volume={24 5-6},
  pages={363-74}
}
Since the first experimental demonstration that a drug of abuse supports instrumental behavior, drugs have been discussed in the context of their rewarding effects, which are assumed to drive and maintain drug-taking behavior. Indeed, drug reward has been fundamental in the formulation of most models of drug use, abuse, and addiction. Over the last several decades, however, drugs of abuse have been increasingly recognized as complex pharmacological compounds producing multiple stimulus effects… CONTINUE READING
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