• DOI:10.1038/20178
Corpus ID: 4403725

The role of the anterior prefrontal cortex in human cognition

@article{Koechlin1999TheRO,
  title={The role of the anterior prefrontal cortex in human cognition},
  author={E. Koechlin and G. Basso and P. Pietrini and Seth Panzer and J. Grafman},
  journal={Nature},
  year={1999},
  volume={399},
  pages={148-151}
}

E. Koechlin, G. Basso, +2 authors J. Grafman

Published 1999

Psychology, Medicine

Nature

Complex problem-solving and planning involve the most anterior part of the frontal lobes including the fronto-polar prefrontal cortex (FPPC), which is especially well developed in humans compared with other primates,. The specific role of this region in human cognition, however, is poorly understood. Here we show, using functional magnetic resonance imaging, that bilateral regions in the FPPC alone are selectively activated when subjects have to keep in mind a main goal while performing… CONTINUE READING

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