The role of the alpha-adrenergic receptor in the leg vasoconstrictor response to orthostatic stress.

@article{Kooijman2009TheRO,
  title={The role of the alpha-adrenergic receptor in the leg vasoconstrictor response to orthostatic stress.},
  author={Miriam Kooijman and Gerard A P J M Rongen and P. G. F. M. Smits and H J M van Kuppevelt and Maria T E Hopman},
  journal={Acta physiologica},
  year={2009},
  volume={195 3},
  pages={357-66}
}
AIM The prompt increase in peripheral vascular resistance, mediated by sympathetic alpha-adrenergic stimulation, is believed to be the key event in blood pressure control during postural stress. However, despite the absence of central sympathetic control of the leg vasculature, postural leg vasoconstriction is preserved in spinal cord-injured individuals (SCI). This study aimed at assessing the contribution of both central and local sympathetically induced alpha-adrenergic leg vasoconstriction… CONTINUE READING