The role of the T-helper/T-suppressor ratio in the adaptive immune response: a dynamical model

  title={The role of the T-helper/T-suppressor ratio in the adaptive immune response: a dynamical model},
  author={Alessia Annibale and Luise Dziobek-Garrett and H Tari},
  journal={Journal of Physics A: Mathematical and Theoretical},
Recent experimental studies have suggested the ratio between T-helper and T-suppressor lymphocytes as an index of immunosuppression in HIV, cancer, immunosenescence and inflammatory and auto-immune diseases. However, a quantitative understanding of the impact of this ratio on the immune response has lagged behind data and its validity as a tool for prognostic monitoring or therapeutic target remains an open question. In this work, we use statistical physics and dynamical systems approaches to… 
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