Corpus ID: 82250784

The role of the Polycomb protein L3MBTL1 in hematopoiesis

  title={The role of the Polycomb protein L3MBTL1 in hematopoiesis},
  author={Fabiana Perna},
  • Fabiana Perna
  • Published 2013
  • Biology
  • Acquired aplastic anemia (AA) is the typical bone marrow failure syndrome characterized by an empty bone marrow; an immune-mediated pathophysiology has been demonstrated by experimental works as well as by clinical observations. Immunusuppressive therapy (IST) is a key treatment strategy for aplastic anemia; since 20 years the standard IST for AA patients has been anti-thymocyte globuline (ATG) plus cyclosporine A (CyA), which results in response rates ranging between 50% and 70%, and even… CONTINUE READING

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