The role of the Panton-Valentine leucocidin toxin in staphylococcal disease: a systematic review and meta-analysis

@inproceedings{Shallcross2013TheRO,
  title={The role of the Panton-Valentine leucocidin toxin in staphylococcal disease: a systematic review and meta-analysis},
  author={Laura J Shallcross and Ellen B Fragaszy and Anne M Johnson and Andrew C Hayward},
  booktitle={The Lancet. Infectious diseases},
  year={2013}
}
BACKGROUND Invasive community-onset staphylococcal disease has emerged worldwide associated with Panton-Valentine leucocidin (PVL) toxin. Whether PVL is pathogenic or an epidemiological marker is unclear. We investigate the role of PVL in disease, colonisation, and clinical outcome. METHODS We searched Medline and Embase for original research reporting the prevalence of PVL genes among Staphylococcus aureus pneumonia, bacteraemia, musculoskeletal infection, skin and soft-tissue infection, or… CONTINUE READING
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