The role of the GATA2 transcription factor in normal and malignant hematopoiesis.

Abstract

Hematopoiesis involves an elaborate regulatory network of transcription factors that coordinates the expression of multiple downstream genes, and maintains homeostasis within the hematopoietic system through the accurate orchestration of cellular proliferation, differentiation and survival. As a result, defects in the expression levels or the activity of… (More)
DOI: 10.1016/j.critrevonc.2011.04.007

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