The role of telomerase protein TERT in Alzheimer's disease and in tau-related pathology in vitro.

@article{Spilsbury2015TheRO,
  title={The role of telomerase protein TERT in Alzheimer's disease and in tau-related pathology in vitro.},
  author={Alison Spilsbury and Satomi Miwa and Johannes Attems and Gabriele Saretzki},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2015},
  volume={35 4},
  pages={1659-74}
}
The telomerase reverse transcriptase protein TERT has recently been demonstrated to have a variety of functions both in vitro and in vivo, which are distinct from its canonical role in telomere extension. In different cellular systems, TERT protein has been shown to be protective through its interaction with mitochondria. TERT has previously been found in rodent neurons, and we hypothesize that it might have a protective function in adult human brain. Here, we investigated the expression of… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 5 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 93 references

Similar Papers

Loading similar papers…