The role of survivin in the resistance of endometriotic stromal cells to drug-induced apoptosis.

  title={The role of survivin in the resistance of endometriotic stromal cells to drug-induced apoptosis.},
  author={Ayako Watanabe and Fuminori Taniguchi and Masao Izawa and Kana Suou and Takashi Uegaki and Eri Takai and Naoki Terakawa and Tasuku Harada},
  journal={Human reproduction},
  volume={24 12},
BACKGROUND Decreased susceptibility of endometrial tissue to apoptosis may contribute to the pathogenesis of endometriosis. We investigate the role of survivin in the pathophysiology of endometriosis through the ability of ectopic and eutopic endometrial stromal cells (ESCs) to resist apoptosis. METHODS Ectopic ESCs were obtained from ovarian chocolate cysts in patients undergoing laparoscopic surgery (n = 22). Eutopic ESCs were isolated from endometrial tissue of cyclic premenopausal women… CONTINUE READING

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