The role of sulfation in thyroid hormone metabolism

@article{Visser1990TheRO,
  title={The role of sulfation in thyroid hormone metabolism},
  author={Thomas Jakob Visser and Joop C. J. van Buuren and Marja Rutgers and Sebo Jan Eelkman Rooda and Wouter W. de Herder},
  journal={Trends in Endocrinology & Metabolism},
  year={1990},
  volume={1},
  pages={211-218}
}
Sulfate conjugation is a significant metabolic reaction for thyroxine and especially so for triiodothyronine and lower iodothyronines in rats. Triiodothyronine sulfation has also been demonstrated in humans. Sulfation accelerates the deiodinative breakdown of iodothyronines by the type I iodothyronine deiodinase in liver and thus represents a rate-limiting step in one of the elimination pathways of thyroid hormone. 
BETA

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 11 CITATIONS

Characterization of human iodothyronine sulfotransferases.

  • The Journal of clinical endocrinology and metabolism
  • 1999
VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Similar Papers

Loading similar papers…