The role of stem cell transplantation in multiple myeloma

  title={The role of stem cell transplantation in multiple myeloma},
  author={J-L. Harousseau and Michel Attal},
  journal={Blood reviews},
  volume={16 4},
High-dose therapy with autologous stem cell transplantation (ASCT) has been extensively used in the past 15 years in multiple myeloma. The IFM 90 trial has shown that autologous bone marrow transplantation (BMT) is superior to conventional chemotherapy in terms of response rate, event free survival, overall survival. Several other randomized studies confirm that ASCT yields superior complete remission and event free survival rates. However, the benefit for overall survival is not always… CONTINUE READING