The role of somatostatin analogues in the treatment of refractory diarrhoea.

@article{Farthing1996TheRO,
  title={The role of somatostatin analogues in the treatment of refractory diarrhoea.},
  author={Michael J. G. Farthing},
  journal={Digestion},
  year={1996},
  volume={57 Suppl 1},
  pages={107-13}
}
Octreotide inhibits intestinal motility and secretions of the gastro-intestinal tract and pancreas and mediators of diarrhoea and so is very useful in managing refractory diarrhoea. It is safe and effective in 75-80% of the 10-20% of cancer chemotherapy patients who develop severe diarrhoea, and is useful in the management of persistent diarrhoea associated with neuroendocrine tumours, particularly VIPoma and carcinoid tumours, congenital microvillus atrophy, some patients with the short bowel… CONTINUE READING