The role of sodium and potassium in insulin secretion from rabbit pancreas.

@article{Hales1968TheRO,
  title={The role of sodium and potassium in insulin secretion from rabbit pancreas.},
  author={Charles Nicholas Hales and R. D. G. Milner},
  journal={The Journal of physiology},
  year={1968},
  volume={194 3},
  pages={725-43}
}
1. Insulin secretion from pieces of rabbit pancreas incubated in vitro was studied in media of different ionic composition and in response to different substances added to the media.2. Experiments were performed which demonstrated that a sodium pump played a role in insulin secretion and that inhibition of the pump by ouabain, or by the omission of extracellular potassium, stimulated insulin secretion.3. A rise in extracellular potassium concentration stimulated insulin secretion independently… CONTINUE READING
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