The role of small molecules in musculoskeletal regeneration.

@article{Lo2012TheRO,
  title={The role of small molecules in musculoskeletal regeneration.},
  author={Kevin W. H. Lo and Keshia M. Ashe and Ho Man Kan and Cato Laurencin},
  journal={Regenerative medicine},
  year={2012},
  volume={7 4},
  pages={
          535-49
        }
}
The uses of bone morphogenetic proteins and parathyroid hormone therapeutics are fraught with several fundamental problems, such as cost, protein stability, immunogenicity, contamination and supraphysiological dosage. These downsides may effectively limit their more universal use. Therefore, there is a clear need for alternative forms of biofactors to obviate the drawbacks of protein-based inductive factors for bone repair and regeneration. Our group has studied small molecules with the… CONTINUE READING
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