The role of silicon in osteoblast-like cell proliferation and apoptosis.

@article{Shie2011TheRO,
  title={The role of silicon in osteoblast-like cell proliferation and apoptosis.},
  author={Ming-You Shie and Shinn-Jyh Ding and Hsien-Chang Chang},
  journal={Acta biomaterialia},
  year={2011},
  volume={7 6},
  pages={2604-14}
}
The optimal concentration at which Si induces cell functions has not been fully elucidated. In the present study the effects of Si concentration (0-6 mM) on the biological functions of MG63 cells were investigated. Cell proliferation in the presence of 2 mM Si- and 4 mM Si-containing media progressively increased with culture time, whereas that of 6mM Si treated MG63 cells was significantly (P<0.05) reduced. The unusually high Si concentration (6 mM) induced a significant (P<0.05) increase in… CONTINUE READING

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