Corpus ID: 26961739

The role of silicic acid in the renal excretion of aluminium.

  title={The role of silicic acid in the renal excretion of aluminium.},
  author={J. P. Bellia and James Derek Birchall and Norman Bryson Roberts},
  journal={Annals of clinical and laboratory science},
  volume={26 3},
The chemical affinity of silicic acid for aluminium (AI) has been shown to reduce the bioavailability of AI in studies of human gastrointestinal (GI) absorption. Investigations were carried out to ascertain whether or not similar interactions may also enhance the renal excretion of AI by assessing the urinary output of both elements. Healthy individuals given monosilicic acid as naturally found in beer, excreted the majority of the silicic acid content (mean 56 percent) within 8 hours… Expand
Silicic acid: its gastrointestinal uptake and urinary excretion in man and effects on aluminium excretion.
The results suggest that orthosilicic acid is readily absorbed from the gastrointestinal tract of man and then readily excreted in urine, suggesting high renal filterability. Expand
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Further studies on the interrelationship of aluminum and silicon in patients receiving aluminum hydroxide therapy for dyspepsia and factors that relate to the solubilization of aluminum
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The silicon link between aluminium and Alzheimer's disease.
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Silicic Acid and Beer Consumption Reverses the Metal Imbalance and the Prooxidant Status Induced by Aluminum Nitrate in Mouse Brain.
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Oligomeric but not monomeric silica prevents aluminum absorption in humans.
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In healthy subjects (presumably in Si balance), the ingestion of a soluble dose of dietary Si results in the same quantity being excreted within 24 h, and isotopic studies are now merited. Expand


Effect of silicon on gastrointestinal absorption of aluminium
Results indicate that dissolved Si is an important factor in limiting the absorption of dietary Al in healthy volunteers using isotopic 26Al tracer administered orally to five healthy volunteers in the presence and absence of Si. Expand
Acute toxicity of aluminium to fish eliminated in silicon-rich acid waters
AN increased level of aluminium in acidified natural waters is a primary cause of fish death from damage to gill epithelia and loss of osmoregulatory capacity1–4. Aluminium toxicity depends on theExpand
Aluminium transport in blood serum. Binding of aluminium by human transferrin in the presence of human albumin and citrate.
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Renal handling of aluminum in the rat: clearance and micropuncture studies.
Previous uncertainty regarding glomerular ultrafilterability (UF) of aluminum has limited the definition of renal Al handling. Glomerular micropuncture was therefore performed in hydropenicExpand
Silicon measurement in serum and urine by direct current plasma emission spectrometry.
Elemental silicon, present as soluble silicic acid in serum and urine, has been measured by direct current plasma emission spectrometry. The method is precise and accurate, yields a standard curveExpand
An assessment of complex formation between aluminium and silicic acid in acidic solutions
Abstract The extent of the reaction A1 3+ + Si(OH) 4 → AlOSi(OH) 3 2+ + H + has been assessed by measuring the shift in log[H + ] between solutions containing A1(ClO 4 ) 3 , HClO 4 , and NaClO 4 withExpand
Effect of citrate infusion on urinary aluminium excretion in the rat.
Among the experimental rats, there was no significant change in urine flow, glomerular filtration rate, plasma and urinary aluminium and citrate level or plasma aluminium level among the control and experimental rats. Expand
Renal handling of silicon in normals and patients with renal insufficiency.
It is concluded that renal insufficiency does not alter the tubular handling of silicon and that regulatory control of silicon excretion is unlikely. Expand
Effect of fiber from fruits and vegetables on metabolic responses of human subjects, II. Calcium, magnesium, iron, and silicon balances.
Calcium magnesium, and silicon balances were significantly lower on the high than on the low fiber diet (P less than 0.01). Expand
The toxicity of aluminium and the effect of silicon on its b ioavailability
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