Corpus ID: 26961739

The role of silicic acid in the renal excretion of aluminium.

@article{Bellia1996TheRO,
  title={The role of silicic acid in the renal excretion of aluminium.},
  author={J. P. Bellia and James Derek Birchall and Norman Bryson Roberts},
  journal={Annals of clinical and laboratory science},
  year={1996},
  volume={26 3},
  pages={
          227-33
        }
}
The chemical affinity of silicic acid for aluminium (AI) has been shown to reduce the bioavailability of AI in studies of human gastrointestinal (GI) absorption. Investigations were carried out to ascertain whether or not similar interactions may also enhance the renal excretion of AI by assessing the urinary output of both elements. Healthy individuals given monosilicic acid as naturally found in beer, excreted the majority of the silicic acid content (mean 56 percent) within 8 hours… Expand
Silicic acid: its gastrointestinal uptake and urinary excretion in man and effects on aluminium excretion.
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The results suggest that orthosilicic acid is readily absorbed from the gastrointestinal tract of man and then readily excreted in urine, suggesting high renal filterability. Expand
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The use of 32Si as a tracer in a human uptake experiment to determine a gastrointestinal uptake factor for silicic acid, and to elucidate the kinetics of renal elimination, establishes a lower limit for gastrointestinal absorption. Expand
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The results of a number of studies suggest that dietary silicon supplementation could be of therapeutic value for preventing chronic aluminum accumulation in the brain, and hence, be a potential therapy for AD. Expand
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Administration of Al(NO3)3 induced metal imbalance, inflammation, and antioxidant status impairment in the brain and those effects were blocked to a significant extent by silicic acid and beer administration. Expand
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