The role of shed placental DNA in the systemic inflammatory syndrome of preeclampsia.

@article{Hartley2015TheRO,
  title={The role of shed placental DNA in the systemic inflammatory syndrome of preeclampsia.},
  author={James Hartley and Brian J Ferguson and Ashley Moffett},
  journal={American journal of obstetrics and gynecology},
  year={2015},
  volume={213 3},
  pages={268-77}
}
Preeclampsia is a syndrome occurring only in pregnancy characterized by systemic maternal inflammation and associated with the presence of the placenta. How these 2 aspects of the disease are linked has been the subject of numerous theories and ideas. Recently, there has been increasing interest in DNA shed from the placenta into the maternal circulation as a potential agent initiating the inflammatory response. This review will discuss the current evidence and future directions for placental… CONTINUE READING
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