The role of sex steroids in the oxytocin hormone system

@article{Ivell1999TheRO,
  title={The role of sex steroids in the oxytocin hormone system},
  author={Richard Dr Ivell and Norbert Walther},
  journal={Molecular and Cellular Endocrinology},
  year={1999},
  volume={151},
  pages={95-101}
}
The sex steroids and the peptide hormone oxytocin are both ancient modulators of the reproductive system of most metazoan species responsible for tissue differentiation and acute events respectively. In vivo experimentation implies estrogenic control of both the oxytocin (OT) gene and that for its receptor (OTR). Yet neither gene promoter appears able to bind classic estrogen-dependent nuclear receptors (ER) in vitro. The literature is confused by some transfected cell culture experiments which… CONTINUE READING
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