The role of semaphorins and their receptors in vascular development and cancer.

@article{Gu2013TheRO,
  title={The role of semaphorins and their receptors in vascular development and cancer.},
  author={Chenghua Gu and Enrico Giraudo},
  journal={Experimental cell research},
  year={2013},
  volume={319 9},
  pages={1306-16}
}
Semaphorins (Semas) are a large family of traditional axon guidance molecules. Through interactions with their receptors, Plexins and Neuropilins, Semas play critical roles in a continuously growing list of diverse biological systems. In this review, we focus on their function in regulating vascular development. In addition, over the past few years a number of findings have shown the crucial role that Semas and their receptors play in the regulation of cancer progression and tumor angiogenesis… CONTINUE READING
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