The role of rifaximin in the primary prophylaxis of spontaneous bacterial peritonitis in patients with liver cirrhosis.

@article{Hanouneh2012TheRO,
  title={The role of rifaximin in the primary prophylaxis of spontaneous bacterial peritonitis in patients with liver cirrhosis.},
  author={Mohamad A Hanouneh and Ibrahim A. Hanouneh and Jana Ghazi Hashash and Ryan E Law and Jamak Modaresi Esfeh and Roc{\'i}o Ortiz L{\'o}pez and Nyla Hazratjee and Thomas W. Smith and Nizar N. Zein},
  journal={Journal of clinical gastroenterology},
  year={2012},
  volume={46 8},
  pages={709-15}
}
BACKGROUND Primary prophylaxis of spontaneous bacterial peritonitis (SBP) may provide a survival advantage in cirrhotic patients with ascites and has become an integral part of clinical practice. Rifaximin is a poorly absorbable antibiotic with a broad spectrum of antibacterial action and has low risk of introducing bacterial resistance. AIM To determine whether rifaximin is associated with decreasing the risk of SBP and improving transplant-free survival in cirrhotic patients with ascites… CONTINUE READING
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