The role of respiratory muscles in the hyperinflation of bronchial asthma.

@article{Martin1980TheRO,
  title={The role of respiratory muscles in the hyperinflation of bronchial asthma.},
  author={James Martin and Elizabeth Powell and Stephanie A. Shore and Jochen Emrich and L A Engel},
  journal={The American review of respiratory disease},
  year={1980},
  volume={121 3},
  pages={441-7}
}
To examine the mechanism of hyperinflation in bronchial asthma we studied lung and chest wall mechanics in 7 asymptomatic patients in whom progressive bronchoconstriction was induced by doubling the amount of inhaled aerosolized histamine. An increase in pulmonary resistance (RL) from 2.5 +/- 0.3 cmH2O . 1-1 . s (mean, +/- 1 SE) to 12.3 +/- 0.9 cmH2 was associated with a linear increase in functional residual capacity (FRC) up to 74.7 +/- 1.7% of control total lung capacity (TLCc). The mean… CONTINUE READING

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