The role of resistin as a regulator of inflammation: Implications for various human pathologies.

@article{Filkov2009TheRO,
  title={The role of resistin as a regulator of inflammation: Implications for various human pathologies.},
  author={M{\'a}ria Filkov{\'a} and Martin Haluz{\'i}k and S. Kirsten Gay and Ladislav {\vS}enolt},
  journal={Clinical immunology},
  year={2009},
  volume={133 2},
  pages={157-70}
}
Resistin was originally described as an adipocyte-secreted peptide that induced insulin resistance in rodents. Increasing evidence indicates its important regulatory roles in various biological processes, including several inflammatory diseases. Further studies have shown that resistin in humans, in contrast to its production by adipocytes in mice, is synthesized predominantly by mononuclear cells both within and outside adipose tissue. Possible roles for resistin in obesity-related subclinical… CONTINUE READING