The role of receptor binding specificity in interspecies transmission of influenza viruses.

@article{Imai2012TheRO,
  title={The role of receptor binding specificity in interspecies transmission of influenza viruses.},
  author={Masaki Imai and Yoshihiro Kawaoka},
  journal={Current opinion in virology},
  year={2012},
  volume={2 2},
  pages={160-7}
}
Influenza A virus infection begins with the binding of the hemagglutinin (HA) glycoprotein to sialic acid-containing receptors on the surface of the target cell. Avian influenza viruses, including avian H5N1, H7, and H9N2 viruses, can occasionally cross the species barrier and infect humans; however, these viruses do not spread efficiently from person to person, perhaps, partly, owing to differences in the receptor-binding specificities of human and avian influenza viruses. The HAs of avian… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS