The role of protein kinase A in the ethanol-induced increase in spontaneous GABA release onto cerebellar Purkinje neurons.

@article{Kelm2008TheRO,
  title={The role of protein kinase A in the ethanol-induced increase in spontaneous GABA release onto cerebellar Purkinje neurons.},
  author={Mary Katherine Kelm and Hugh E. Criswell and George R. Breese},
  journal={Journal of neurophysiology},
  year={2008},
  volume={100 6},
  pages={3417-28}
}
Ethanol increases miniature inhibitory postsynaptic current frequency and decreases the paired-pulse ratio, which suggests that ethanol increases both spontaneous and evoked GABA release, respectively. We have shown previously that ethanol increases GABA release at the rat interneuron-Purkinje cell synapse and that this ethanol effect involves calcium… CONTINUE READING