The role of prostaglandins in the bradykinin-induced activation of serosal afferents of the rat jejunum in vitro.

@article{Maubach1999TheRO,
  title={The role of prostaglandins in the bradykinin-induced activation of serosal afferents of the rat jejunum in vitro.},
  author={Karen Maubach and David Grundy},
  journal={The Journal of physiology},
  year={1999},
  volume={515 ( Pt 1)},
  pages={277-85}
}
1. This study was performed to elucidate the role of prostaglandins in the action of bradykinin on serosal afferent neurones supplying the rat jejunum. Extracellular recordings of multi-unit activity were made from serosal afferents in isolation, using a novel in vitro preparation. The discharge of single afferents within the multi-unit recording was monitored using waveform discrimination software. 2. All afferents tested were both mechano- and capsaicin sensitive. Application of bradykinin… CONTINUE READING

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