The role of propionate and acetate in the control of food intake in sheep.

@article{Farningham1993TheRO,
  title={The role of propionate and acetate in the control of food intake in sheep.},
  author={D A Farningham and C C Whyte},
  journal={The British journal of nutrition},
  year={1993},
  volume={70 1},
  pages={37-46}
}
Sheep fed ad lib. on a good-quality pelleted diet (g/kg; hay 500, barley 300, molasses, fish meal and minerals) were infused via the hepatic portal vein with mixtures of the sodium salts of volatile fatty acids, acetate and propionate, and a variety of equivalent osmotic loads. Propionate infused at rates between 0.6 and 2.5 mmol/min consistently reduced food intake in a linear, dose-related manner. Propionate infusions resulted in consistent dose-related increases in peripheral venous plasma… CONTINUE READING

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