The role of platelets in mediating a response to human influenza infection

  title={The role of platelets in mediating a response to human influenza infection},
  author={Milka Koupenova and Heather A Corkrey and Olga I. Vitseva and Giorgia Manni and Catherine J Pang and Lauren Clancy and Chang Yao and Jeffrey J. Rade and Daniel A. Levy and Jennifer P Wang and Robert W. Finberg and Evelyn A Kurt-Jones and Jonathan E. Freedman},
  booktitle={Nature Communications},
Influenza infection increases the incidence of myocardial infarction but the reason is unknown. Platelets mediate vascular occlusion through thrombotic functions but are also recognized to have immunomodulatory activity. To determine if platelet processes are activated during influenza infection, we collected blood from 18 patients with acute influenza infection. Microscopy reveals activated platelets, many containing viral particles and extracellular-DNA associated with platelets. To… CONTINUE READING


Publications referenced by this paper.

Acute myocardial infarction after laboratory-confirmed influenza infection

Kwong, C J.
  • N. Engl. J. Med
  • 2018

NETosis markers: Quest for specific, objective, and quantitative markers.

  • Clinica chimica acta; international journal of clinical chemistry
  • 2016

Similar Papers

Loading similar papers…