The role of plasminogen in interleukin-1 mediated cartilage degradation.

Abstract

Explants of 35SO4 labelled rabbit articular cartilage, cultured for 3 days with either 5 X 10(4) rabbit peritoneal cells (PEC) or 1:10 macrophage conditioned medium (MCM), released 30-40% of labelled proteoglycans into the medium while controls released 8-12%. The addition of 1 mM 4 aminophenylmercuric acetate (APMA) or 0.2 U/ml plasminogen increased… (More)

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Cite this paper

@article{Collier1988TheRO, title={The role of plasminogen in interleukin-1 mediated cartilage degradation.}, author={Steven Collier and Peter Ghosh}, journal={The Journal of rheumatology}, year={1988}, volume={15 7}, pages={1129-37} }