The role of pigment epithelium-derived factor in the pathophysiology and treatment of ovarian hyperstimulation syndrome in mice.

@article{Chuderland2013TheRO,
  title={The role of pigment epithelium-derived factor in the pathophysiology and treatment of ovarian hyperstimulation syndrome in mice.},
  author={Dana Chuderland and Ido Ben-ami and Ruth Kaplan-Kraicer and Hadas Grossman and R Ron-el and Ruth Shalgi},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2013},
  volume={98 2},
  pages={E258-66}
}
CONTEXT Ovarian hyperstimulation syndrome (OHSS) is a potentially life-threatening complication of assisted reproduction. OHSS is induced by an ovarian release of vasoactive, angiogenic substances that results in vascular hyperpermeability, leakage, and shift of fluids from blood vessels into the extravascular space with consequent ascites and edema that are attributed to vascular endothelial growth factor (VEGF). OBJECTIVE Our objective was to examine a physiological approach for preventing… CONTINUE READING
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Prevention of the onset of ovarian hyperstimulation syndrome (OHSS) in the rat after ovulation induction with a low molecular weight agonist of the LH receptor compared with hCG and rec-LH

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