The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention


Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors that are involved in regulating glucose and lipid homeostasis, inflammation, proliferation and differentiation. Although all of these functions might contribute to the influence of PPARs in carcinogenesis, there is a distinct need for a review of the literature… (More)
DOI: 10.1038/nrc3214


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