The role of paraventricular nucleus of hypothalamus in stress-ulcer formation in rats.

@article{Zhang1997TheRO,
  title={The role of paraventricular nucleus of hypothalamus in stress-ulcer formation in rats.},
  author={Ji-qiang Zhang and Fang Zheng},
  journal={Brain research},
  year={1997},
  volume={761 2},
  pages={203-9}
}
The rat stress model of restraint and cold water immersion was used to investigate the effect of stimulating the paraventricular nucleus (PVN) of hypothalamus on the development of stress-induced gastric ulceration. The results were (1) electric stimulation of the PVN increased the stress ulceration, while electrolytic lesion of the PVN decreased it; (2) intracerebroventricular injection (i.c.v.) of acetylcholine (Ach) enhanced the effect of PVN stimulation on stress ulcers, and the M-receptor… CONTINUE READING

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