The role of paracetamol and nonsteroidal anti-inflammatory drugs in addition to WHO Step III opioids in the control of pain in advanced cancer. A systematic review of the literature.

@article{Nabal2012TheRO,
  title={The role of paracetamol and nonsteroidal anti-inflammatory drugs in addition to WHO Step III opioids in the control of pain in advanced cancer. A systematic review of the literature.},
  author={Mar{\'i}a Nabal and Silvia Librada and Maria Jose Redondo and Alessandra Pigni and Cinzia Brunelli and Augusto T Caraceni},
  journal={Palliative medicine},
  year={2012},
  volume={26 4},
  pages={
          305-12
        }
}
BACKGROUND Nonsteroidal anti-inflammatory drugs (NSAIDs) and paracetamol are used widely in the management of mild to moderate cancer pain and are frequently combined with opioids in the treatment of moderate to severe pain. AIM To perform a systematic literature review of the evidence of the efficacy and toxicity of NSAIDs or paracetamol added to WHO Step III opioid treatment for cancer pain. DESIGN AND DATA SOURCES A systematic literature review of MedLine, EMBASE and Cochrane Central… CONTINUE READING
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