The role of p53 in determining sensitivity to radiotherapy

@article{Gudkov2003TheRO,
  title={The role of p53 in determining sensitivity to radiotherapy},
  author={Andrei V. Gudkov and Elena A. Komarova},
  journal={Nature Reviews Cancer},
  year={2003},
  volume={3},
  pages={117-129}
}
Ionizing radiation (IR) has proven to be a powerful medical treatment in the fight against cancer. Rational and effective use of its killing power depends on understanding IR-mediated responses at the molecular, cellular and tissue levels. Tumour cells frequently acquire defects in the molecular regulatory mechanisms of the response to IR, which sensitizes… CONTINUE READING