The role of oxidative stress in skeletal muscle injury and regeneration: focus on antioxidant enzymes

@inproceedings{Kozakowska2015TheRO,
  title={The role of oxidative stress in skeletal muscle injury and regeneration: focus on antioxidant enzymes},
  author={Magdalena Kozakowska and Katarzyna Pietraszek-Gremplewicz and Alicja J{\'o}zkowicz and Jozef Dulak},
  booktitle={Journal of Muscle Research and Cell Motility},
  year={2015}
}
Reactive oxygen species (ROS) are generated in skeletal muscle both during the rest and contractile activity. Myogenic cells are equipped with antioxidant enzymes, like superoxide dismutase, catalase, glutathione peroxidase, γ-glutamylcysteine synthetase and heme oxygenase-1. These enzymes not only neutralise excessive ROS, but also affect myogenic regeneration at several stages: influence post-injury inflammatory reaction, enhance viability and proliferation of muscle satellite cells and… CONTINUE READING
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