The role of omega-3 fatty acid receptor GPR120 in insulin resistance.

@article{Oh2014TheRO,
  title={The role of omega-3 fatty acid receptor GPR120 in insulin resistance.},
  author={Da Young Oh and Evelyn Walenta},
  journal={International journal of obesity supplements},
  year={2014},
  volume={4 Suppl 1},
  pages={S14-6}
}
Obesity is the dominant cause of acquired insulin resistance, and it is the epidemic of obesity in the United States that is driving the markedly increasing incidence of type 2 diabetes. Adipocyte dysfunction and chronic low-grade adipose tissue (AT) inflammation are the major causes of insulin resistance. Abnormal accumulation and activation of AT macrophages (ATMs) and abnormal activation of the TLR4-mediated immune responses within ATMs are the key characters of the chronic low-grade AT… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

References

Publications referenced by this paper.
Showing 1-10 of 41 references

Hematopoietic cellspecific deletion of toll - like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in highfatfed mice

  • M Saberi, NB Woods, C deLuca, S Schenk, JC Lu, G Bandyopadhyay
  • Cell Metab
  • 2009

hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity

  • M Saberi, NB Woods, C de Luca, S Schenk, JC Lu, G Bandyopadhyay
  • Cell Metab 2007;
  • 2009

Similar Papers

Loading similar papers…