The role of nutritional factors in the aetiology of neural tube defects

  title={The role of nutritional factors in the aetiology of neural tube defects},
  author={Carol Bower and Fiona J. Stanley},
  journal={Journal of Paediatrics and Child Health},
Maternal diet has long been suspected as a risk factor for neural tube defects. Following the Second World War, at a time of severe food deprivation, there was an increase in malformations of the central nervous system (mainly anencephaly and spina bifida) in several European countries.’ An excess of spina bifida and hydrocephalus also occurred in the cohort of Dutch boys exposed in ufero in early gestation to the Dutch Hunger Winter of 1 944-45.2 Several dietary factors have been associated… Expand

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