The role of nutrition in brain development.

  title={The role of nutrition in brain development.},
  author={Pierre Ren{\'e} Guesry},
  journal={Preventive medicine},
  volume={27 2},
  • P. Guesry
  • Published 1 March 1998
  • Medicine
  • Preventive medicine
Common sense always links good nutrition with optimal development of infants and, particularly, of brain development. Fortunately, brain development is rather resistant to nutritional deficiencies, provided that the psychomotor stimulation of the baby is adequate, as shown by many authors in the case of global protein energy malnutrition. For two types of micronutrient deficiency, those of iron and long-chain polyunsaturated fatty acids, it is easier to isolate the role of micronutrient… 

The Role of Early Nutritional Deficiencies in the Development of Psychopathology

The authors present a review of the studies directly linking early malnutrition to the later development of various types of psychopathologies including schizophrenia spectrum disorders, antisocial behavior and other externalizing disorders, substance use disorders, and internalizing disorders such as depression.

Role of micronutrients for physical growth and mental development

It has been shown that it is not possible to meet 100% requirements of recommended dietary allowances (RDA’s) of micronutrients from dietary sources alone and most preschool children need administration of nutritional supplements to optimize their genetic potential for physical growth and mental development.

Brain iron deficiency and excess; cognitive impairment and neurodegenration with involvement of striatum and hippocampus

  • M. Youdim
  • Biology, Psychology
    Neurotoxicity Research
  • 2009
It is shown that in this condition it is the brain striatal dopaminergic-opiate system which becomes defective, resulting in alterations in circadian behaviours, cognitive impairment and neurochemical changes closely associated with them.

Has an aquatic diet been necessary for hominin brain evolution and functional development?

There is no evidence that human diets based on terrestrial food chains with traditional nursing practices fail to provide adequate levels of DHA or othern-3 fatty acids, and the hypothesis that DHA has been a limiting resource in human brain evolution must be considered to be unsupported.

Nutrition and neurodevelopment: mechanisms of developmental dysfunction and disease in later life

A major aim of future research should be to elucidate the molecular mechanisms underlying nutritionally-induced impairment of neurodevelopment and specifically to determine the mechanisms by which early nutritional experience affects later cognitive performance.

Neuroimaging of the Developing Brain and Impact of Nutrition.

  • S. Deoni
  • Psychology, Biology
    Nestle Nutrition Institute workshop series
  • 2018
The current understanding of early-life nutrition and its effects on the developing brain as detailed through neuroimaging is overview, showing that nutrition is a critical and readily modifiable influence that can profoundly impact early brain maturation.

Maternal dietary tryptophan deficiency alters cardiorespiratory control in rat pups.

Important interactions between nutrition, brain stem physiology, and age that are potentially relevant to understanding 5-HT deficiency in the sudden infant death syndrome are indicated.

Maternal intake of cashew nuts accelerates reflex maturation and facilitates memory in the offspring





An experimental and ecologic study concerned with estimating some of the effects which malnutrition in early childhood may have upon neurointegrative functioning finds that protein deficiency may result in structural lesions of the nervous system.

The influence of early malnutrition on subsequent behavioral development. II. Classroom behavior.

The classroom behaviors of 129 Barbadian children who suffered from moderate-severe protein-energy malnutrition in the first year of life were compared with those observed in children with no history of malnutrition, demonstrating that the previously malnourished children had attention deficits, reduced social skills, poorer physical appearance and emotional instability when compared to the matched comparison children.

Iron deficiency anemia: adverse effects on infant psychomotor development.

When iron deficiency progresses to anemia, but not before, adverse influences in the performance of developmental tests appear and persist for at least 3 months despite correction of anemia with iron therapy, suggesting prevention of iron deficiency anemia in early infancy becomes the only way to avoid them.

Fatty acid composition of brain, retina, and erythrocytes in breast- and formula-fed infants.

The higher concentration of DHA in brains of breast- fed infants may explain the improved neurodevelopment reported in breast-fed compared with formula-fed infants.