The role of novel and known extracellular matrix and adhesion molecules in the homeostatic and regenerative bone marrow microenvironment

@inproceedings{Klamer2014TheRO,
  title={The role of novel and known extracellular matrix and adhesion molecules in the homeostatic and regenerative bone marrow microenvironment},
  author={Sofieke Klamer and Carlijn Voermans},
  booktitle={Cell adhesion & migration},
  year={2014}
}
Maintenance of haematopoietic stem cells and differentiation of committed progenitors occurs in highly specialized niches. The interactions of haematopoietic stem and progenitor cells (HSPCs) with cells, growth factors and extracellular matrix (ECM) components of the bone marrow (BM) microenvironment control homeostasis of HSPCs. We only start to understand the complexity of the haematopoietic niche(s) that comprises endosteal, arterial, sinusoidal, mesenchymal and neuronal components. These… CONTINUE READING

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