The role of non-synaptic extracellular glutamate.

  title={The role of non-synaptic extracellular glutamate.},
  author={Manuel Rodriguez and Magdalena Sabat{\'e} and Clara Rodriguez-Sabate and Ingrid Morales},
  journal={Brain research bulletin},
Although there are some mechanisms which allow the direct crossing of substances between the cytoplasm of adjacent cells (gap junctions), most substances use the extracellular space to diffuse between brain cells. The present work reviews the behavior and functions of extracellular glutamate (GLU). There are two extracellular pools of glutamate (GLU) in the brain, a synaptic pool whose functions in the excitatory neurotransmission has been widely studied and an extrasynaptic GLU pool although… CONTINUE READING