The role of non-aromatizable testosterone metabolite in metabolic pathways.

Abstract

Dihydrotestosterone (DHT) originates via irreversible reduction of testosterone by catalytic activity of 5alpha-reductase enzyme and it is demonstratively the most effective androgen. Androgens influence adipose tissue in men either directly by stimulation of the androgen receptor or indirectly, after aromatization, by acting at the estrogen receptor. DHT… (More)

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@article{Dukov2011TheRO, title={The role of non-aromatizable testosterone metabolite in metabolic pathways.}, author={Michaela Du{\vs}kov{\'a} and Hana Posp{\'i}{\vs}ilov{\'a}}, journal={Physiological research}, year={2011}, volume={60 2}, pages={253-61} }