The role of nitric oxide in the pathophysiology of intimal hyperplasia.

@article{Ahanchi2007TheRO,
  title={The role of nitric oxide in the pathophysiology of intimal hyperplasia.},
  author={Sadaf Sadie Ahanchi and Nick D. Tsihlis and Melina R Kibbe},
  journal={Journal of vascular surgery},
  year={2007},
  volume={45 Suppl A},
  pages={A64-73}
}
Since its discovery, nitric oxide (NO) has emerged as a biologically important molecule and was even named Molecule of the Year by Science magazine in 1992. Specific to our interests, NO has been implicated in the regulation of vascular pathology. This review begins with a summary of the molecular biology of NO, from its discovery to the mechanisms of endogenous production. Next, we turn our attention to describing the arterial injury response of neointimal hyperplasia, and we review the role… CONTINUE READING