The role of nitric oxide in modulating brain activity and blood flow during seizure.

Abstract

The role played by nitric oxide (NO) in modulating seizure activity and cerebral blood flow (CBF) during seizures was investigated in rats. Seizures were induced with bicuculline (a GABA antagonist, 1.2 mg kg-1, i.v.). Each animal was subjected to an initial bicuculline-induced seizure followed by treatment with either L-nitroarginine (L-NA, a NO synthase… (More)

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@article{Theard1995TheRO, title={The role of nitric oxide in modulating brain activity and blood flow during seizure.}, author={Michel A Theard and Verna L. Baughman and Q. Wang and Dale A. Pelligrino and Renate Albrecht}, journal={Neuroreport}, year={1995}, volume={6 6}, pages={921-4} }