The role of neurotrophins during early development.

@article{Bernd2008TheRO,
  title={The role of neurotrophins during early development.},
  author={Paulette Bernd},
  journal={Gene expression},
  year={2008},
  volume={14 4},
  pages={
          241-50
        }
}
The effects of neurotrophins during the middle and late stages of development are well known. It was previously thought that neurotrophins had no role during early development, but this is not the case and is the subject of this review article. The earliest neurotrophin receptor expressed is that for neurotrophin-3 (NT-3). TrkC is detected in the neural plate and is present in the neural tube. Initially, the distribution of TrkC is homogenous, but it becomes localized to specific regions of the… CONTINUE READING

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