The role of myeloid cells in cancer therapies
@article{Engblom2016TheRO, title={The role of myeloid cells in cancer therapies}, author={Camilla Engblom and Christina Pfirschke and Mikael J. Pittet}, journal={Nature Reviews Cancer}, year={2016}, volume={16}, pages={447-462} }
Recent clinical trials have demonstrated the ability to durably control cancer in some patients by manipulating T lymphocytes. These immunotherapies are revolutionizing cancer treatment but benefit only a minority of patients. It is thus a crucial time for clinicians, cancer scientists and immunologists to determine the next steps in shifting cancer treatment towards better cancer control. This Review describes recent advances in our understanding of tumour-associated myeloid cells. These cells…
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