The role of monocytes and inflammation in the pathophysiology of heart failure.

@article{Wrigley2011TheRO,
  title={The role of monocytes and inflammation in the pathophysiology of heart failure.},
  author={Benjamin J Wrigley and Gregory Y. H. Lip and E Shantsila},
  journal={European journal of heart failure},
  year={2011},
  volume={13 11},
  pages={1161-71}
}
There is growing evidence to support an important role of inflammation in the underlying pathophysiology of heart failure (HF). Indeed, inflammatory cytokine levels are well recognized to be increased in patients with left ventricular dysfunction and appear to have prognostic implications. Monocytes play a pivotal role in the inflammatory cascade and are a major source of both pro- and anti-inflammatory cytokines. They are intimately involved in tissue damage and repair and an imbalance of… CONTINUE READING
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