The role of mitomycin C in preventing synechia and stenosis after endoscopic sinus surgery.

@article{Anand2004TheRO,
  title={The role of mitomycin C in preventing synechia and stenosis after endoscopic sinus surgery.},
  author={Vijay Karan Singh Anand and Abtin Tabaee and Ashutosh Kacker and Jason G. Newman and Clark Huang},
  journal={American journal of rhinology},
  year={2004},
  volume={18 5},
  pages={311-4}
}
BACKGROUND Synechia and stenosis formation after endoscopic sinus surgery (ESS) represents a potential source of surgical failure. Mitomycin C (MMC) has been used successfully in other fields to decrease postoperative scar formation. We hypothesize that the topical application of MMC reduces the incidence of stenosis and synechia formation after ESS. METHODS This study is a randomized, controlled, single-blinded study based in a tertiary care teaching hospital. After routine ESS, a pledget… CONTINUE READING