The role of mitochondrial bioenergetics and reactive oxygen species in coronary collateral growth.

@article{Pung2013TheRO,
  title={The role of mitochondrial bioenergetics and reactive oxygen species in coronary collateral growth.},
  author={Yuh Fen Pung and Wai Johnn Sam and James P. Hardwick and Liya Yin and Vahagn A Ohanyan and Suzanna Logan and Lola Di Vincenzo and William M. Chilian},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2013},
  volume={305 9},
  pages={
          H1275-80
        }
}
Coronary collateral growth is a process involving coordination between growth factors expressed in response to ischemia and mechanical forces. Underlying this response is proliferation of vascular smooth muscle and endothelial cells, resulting in an enlargement in the caliber of arterial-arterial anastomoses, i.e., a collateral vessel, sometimes as much as an order of magnitude. An integral element of this cell proliferation is the process known as phenotypic switching in which cells of a… CONTINUE READING

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