The role of mitochondrial K(ATP) channels in antiarrhythmic effects of ischaemic preconditioning in dogs.

@article{Vgh2002TheRO,
  title={The role of mitochondrial K(ATP) channels in antiarrhythmic effects of ischaemic preconditioning in dogs.},
  author={{\'A}gnes V{\'e}gh and James Roy Parratt},
  journal={British journal of pharmacology},
  year={2002},
  volume={137 7},
  pages={
          1107-15
        }
}
1. In the canine a single brief (5 min) coronary artery occlusion protects the myocardium against the severe ventricular arrhythmias and reduces the ischaemic changes that result from a subsequent, more prolonged (25 min) occlusion. The main purpose of the present study was to examine whether mitochondrial K(ATP) channels are involved in this protection. 2. In chloralose-urethane anaesthetized dogs, preconditioning (PC) was induced by a single 5 min period occlusion of the left anterior… CONTINUE READING
Highly Cited
This paper has 36 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 38 references

Preconditioning limits mitochondrial Ca(2+) during ischemia in rat hearts: role of K(ATP) channels.

American journal of physiology. Heart and circulatory physiology • 2001
View 1 Excerpt