The role of mitochondria in the life of the nematode, Caenorhabditis elegans.

  title={The role of mitochondria in the life of the nematode, Caenorhabditis elegans.},
  author={William Y Tsang and Bernard D Lemire},
  journal={Biochimica et biophysica acta},
  volume={1638 2},
Mitochondria are essential organelles involved in energy metabolism via oxidative phosphorylation. They play a vital role in diverse biological processes such as aging and apoptosis. In humans, defects in the mitochondrial respiratory chain (MRC) are responsible for or associated with a bewildering variety of diseases. The nematode Caenorhabditis elegans is a simple animal and a powerful genetic and developmental model system. In this review, we discuss how the nematode model system has… CONTINUE READING


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